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Toxicological tests have been performed on animals
to establish amount of additive likely to be harmful to
humans
Maximum
dose of the additive is identified, which gives NO observable
adverse effect each day over the animals' lifetime. About
100 times less than this figure becomes acceptable
daily intake for humans.
Safety assessments are done on individual additives,
not a combination of additives (which is how they are
consumed in real life).
Food
additives have generic terms or classes e.g colouring;
label must include specific type of colouring (e.g tartrazine)
by name or number due to food sensitivities.
Nobody
knows the long-term effects of eating a cocktail
of different additives
Some of the additives that cause adverse reactions
appear to be added largely for marketing advantage e.g
coloured icecreams
Labels should include all additives, whatever their
quantity - helps consumers who wish to avoid them;
small amounts of hidden additives can add up, becoming
significant for sensitive people.

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